Chelation therapy

A chelator is a substance that is NOT metabolized by the body and excreted as it entered without alteration, except that it combines metals in its way and excrete them in the urine. Oral chelation is the process whereby certain chelating agents are ingested, in order to bind strongly or chelate metals within the body, using several chemical bonds, thus rendering the metallic ion much less chemically active and allowing for harmless excretion.

A true chelator is identified by the presence of “Two di-thiol groups”. Many health practitioners and doctors use compounds such as: chlorella, cysteine, NAC and glutathione, claiming they are chelators. But these are ineffective substances as chelators because they are not contain two or more binding groups (Dithiol groups), rather they contain only one thiol group. These compounds can make matters worse by causing redistribution of stored metals, by mobilizing them from their storage sites, but failing to bind and excrete them. This is like stirring up a hornets nest

Chelating agents are used in medicine to treat “Heavy metal toxicity”, which include: aluminum, iron, copper, mercury, arsenic, nickel, and even calcium. The most common chelating agents used are:

1. Alpha lipoic acid (ALA): ALA is best used to chelate: Arsenic (Best), Cadmium, Mercury, Palladium, Platinum toxicities. It crosses blood brain barrier

2. DMSA (Dimercaptosuccinic acid): DMSA is a water-soluble, sulfhydryl-containing compound which is an effective oral chelator of heavy metals. Bile excretion is the main route of elimination to many heavy metals (Mercury, lead, copper, cadmium, arsenic). DMSA is best to chelate: Bisthmus, Cadmium, Gold, lead (Best), Platinum, Nickel, Palladium toxicities. It does NOT cross blood brain barrier

3. EDTA (Ethylenediamine tetraacetic acid): EDTA is a popular metal chelator that can be used to treat many conditions including: atherosclerosis, hypertension,  renal failure (Lead toxicity), and many neurodegenerative disorders known to be due to heavy metal toxicity

EDTA was previously promoted as being good for removing calcium plaques in blood vessels. It is now suggested that it does not remove calcium plaques, but instead removes metals from the vessel lining (epithelial) receptor sites, thereby freeing up receptor sites to receive more nitric oxide, which was previously blocked by metals

EDTA can be given orally and intravenously and it is best used to chelate: Gadolinium, Lead (Alternative), Beryllium toxicities. It does NOT cross blood brain barrier

 

Selected references

1. Cutler AH. Amalgam Illness, Diagnosis and Treatment : What You Can Do to Get Better, How Your Doctor Can Help. 1999; Self-publishing; 1st edition

http://www.amazon.com/Amalgam-Illness-Diagnosis-Treatment-Better/dp/0967616808/ref=sr_1_1?s=books&ie=UTF8&qid=1439360828&sr=1-1&keywords=Andy+Cutler

2. Cutler AH. Hair Test Interpretation: Finding Hidden Toxicities. 2004; Self-publishing; 1st edition

http://www.amazon.com/Hair-Test-Interpretation-Finding-Toxicities/dp/0967616816/ref=pd_sim_14_1?ie=UTF8&refRID=1E0N0FTSMBM5NTAP563E

3. Brown DJ, Gordon G. Detox with Oral Chelation: Protecting Yourself from Lead, Mercury, & Other Environmental Toxins. 2007; Smart Publications; 1st edition

http://www.amazon.com/Detox-Oral-Chelation-Protecting-Environmental/dp/1890572209/ref=sr_1_2?s=books&ie=UTF8&qid=1439361371&sr=1-2&keywords=EDTA

4. Gordon GF et al. EDTA chelation therapy for atherosclerosis: history and mechanisms of action. Osteopath Ann, 1976; 4:38-62

5. Riordon HD et al. Another look at renal function and the EDTA treatment process. J Orthomolecular Med. 1987;2:185-187